Searchable abstracts of presentations at key conferences in endocrinology

ea0019p282 | Reproduction | SFEBES2009

Clot structure and fibrinolysis in individuals with polycystic ovary syndrome: the effects of metformin, orlistat and pioglitazone treatment

Ajjan R , Chow L , Scott E , Carter A , Phoenix F , Grant P , Atkin S

Polycystic ovary syndrome (PCOS), which affects 7% of the female population, is associated with established cardiovascular risk factors including obesity, dyslipidaemia and insulin resistance. Thrombus formation represents the final step in the atherothrombotic process and clot structure has been shown to predict the predisposition to cardiovascular events. The aim of the present work was to assess the effects of commonly used therapeutic agents on clot structure and fibrinoly...